Waters Introduces BioResolve Protein A Affinity Columns to Accelerate Antibody Titer Measurement, Enhancing Process Agility and Batch Quality

07.08.2025 - 18:07:50

Waters Corporation Massachusetts

(NYSE:WAT) is a global leader in analytical instruments, separations technologies, and software, serving the life, materials, food, and environmental sciences for over 65 years. Our Company helps ensure the efficacy of medicines, the safety of food and the purity of water, and the quality and sustainability of products used every day. In over 100 countries, our 7,600+ passionate employees collaborate with customers in laboratories, manufacturing sites, and hospitals to accelerate the benefits of pioneering science.

Waters, BioResolve, and MaxPeak are trademarks of Waters Technologies Corporation.

Contact:

Molly Gluck
Head of External Communications
Waters Corporation
Molly_gluck@waters.com
Mobile: +1.617.833.8166

Improved ability to detect antibody at 7x lower concentrations using low-dispersion U(H)PLC allows for titer measurements at least one day earlier based on standard CHO cell line doubling time.Application note 720008775EN: In a well-controlled experiment, the lower limit of quantitation of NISTmAb reference material RM 8671 was 5x-7x lower using the 2.1 x 20 mm and 3.9 x 5 mm BioResolve Protein A Affinity Columns using a low-dispersion UPLC compared to a leading competitor.Application note 720008780EN: Demonstrates the measurement of antibody titer and aggregate analysis in a single run following a direct-connect ProA-SEC method. This launch marks the first set of affinity chromatography columns that Waters has brought to market, in a groundbreaking move as the Company continues to release new products that solve unmet needs in large molecule separations.