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Tagworks Pharmaceuticals Announces FDA Clearance of IND Application and Initiation of Phase 1 Clinical Trial for TGW101 and Appoints Keith Orford, MD, PhD, as Chief Medical Officer

TGW101 is a next-generation, first-in-class ADC targeting TAG-72 with an MMAE payload, developed based on Tagworks proprietary Click-to-Release linker chemistry; TGW101 is the first bioorthogonal, in vivo click chemistry-activated ADC, which enables superior control of tumor payload activityPhase 1 clinical trial of TGW101 initiated; Company plans to enroll up to 50 patients with advanced solid tumors in the U.S.Keith Orford, MD, PhD, brings over three decades of leadership in oncology research and clinical drug development and will oversee an emerging clinical pipeline of novel cancer treatments leveraging Click-to-Release technology, including ADCs and targeted radiopharmaceuticalsView original content:https://www.prnewswire.co.uk/news-releases/tagworks-pharmaceuticals-announces-fda-clearance-of-ind-application-and-initiation-of-phase-1-clinical-trial-for-tgw101-and-appoints-keith-orford-md-phd-as-chief-medical-officer-302433670.html