Supermicro Extends AI and GPU Rack Scale Solutions with Support for AMD Instinct MI300 Series Accelerators
07.08.2025 - 18:03:43Supermicro is also introducing a density optimized 2U liquid-cooled server, the AS –2145GH-TNMR, and a 4U air-cooled server, the AS –4145GH-TNMR, each with 4 AMD Instinct™ MI300A accelerators. The new servers are designed for HPC and AI applications, requiring extremely fast CPU to GPU communication. The APU eliminates redundant memory copies by combining the highest-performing AMD CPU, GPU, and HBM3 memory on a single chip. Each server contains leadership x86 "Zen4" CPU cores for application scale-up. Also, each server includes 512GB of HBM3 memory. In a full rack (48U) solution consisting of 21 2U systems, over 10TB of HBM3 memory is available, as well as 19,152 Compute Units. The HBM3 to CPU memory bandwidth is 5.3 TB/second.
Both systems feature dual AIOMs with 400G Ethernet support and expanded networking options designed to improve space, scalability, and efficiency for high-performance computing. The 2U direct-to-chip liquid-cooled system delivers excellent TCO with over a 35% energy consumption savings based on 21 2U system rack solutions that produce 61,780 watts per rack over 95,256 watts air-cooled rack, as well as a 70% reduction in the number of fans compared to an air cooled system.
"AMD Instinct MI300 Series accelerators deliver leadership performance, both for longstanding accelerated high performance computing applications and for the rapidly growing demand for generative AI," said Forrest Norrod, executive vice president and general manager, Data Center Solutions Business Group, AMD. "We continue to work closely with Supermicro to bring to market leading-edge AI and HPC total solutions based on MI300 Series accelerators and leveraging Supermicro's expertise in system and data center design."
Learn more from Supermicro and AMD experts. View this webinar live or on demand.
For more information, please visit:
Supermicro AMD Accelerator Site
AS -8125GS-TNMR2 (8U w/ MI300x)
AS -2145GH-TNMR (2U LC w/ MI300A)
AS -4145GH-TNMR (4U AC w/ MI300A)
About Super Micro Computer, Inc.
Supermicro (NASDAQ: SMCI) is a global leader in Application-Optimized Total IT Solutions. Founded and operating in San Jose, California, Supermicro is committed to delivering first to market innovation for Enterprise, Cloud, AI, and 5G Telco/Edge IT Infrastructure. We are a Total IT Solutions manufacturer with server, AI, storage, IoT, switch systems, software, and support services. Supermicro's motherboard, power, and chassis design expertise further enable our development and production, enabling next generation innovation from cloud to edge for our global customers. Our products are designed and manufactured in-house (in the US, Taiwan, and the Netherlands), leveraging global operations for scale and efficiency and optimized to improve TCO and reduce environmental impact (Green Computing). The award-winning portfolio of Server Building Block Solutions® allows customers to optimize for their exact workload and application by selecting from a broad family of systems built from our flexible and reusable building blocks that support a comprehensive set of form factors, processors, memory, GPUs, storage, networking, power, and cooling solutions (air-conditioned, free air cooling or liquid cooling).
Supermicro, Server Building Block Solutions, and We Keep IT Green are trademarks and/or registered trademarks of Super Micro Computer, Inc.
AMD, the AMD Arrow logo, AMD Instinct, EPYC and combinations thereof are trademarks of Advanced Micro Devices.
All other brands, names, and trademarks are the property of their respective owners.

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