AMA Approves CPT Codes for Caristo's AI-Powered Heart Disease Risk Stratification and Prevention Technology

CARISTO DIAGNOSTICS United Kingdom England Connecticut United States of America

New CPT codes mark a major step toward making Caristo's CaRi-Heart®—the first AI-powered tool to detect coronary inflammation from routine CT scans—available in everyday clinical careRewriting the rules of cardiac risk assessment, Caristo moves beyond anatomy to reveal the biological drivers of heart disease, helping doctors predict and prevent life-threatening events before symptoms or structural changes appearWith support from medical societies including the American College of Cardiology, Caristo achieved CPT approval well ahead of the CaRi-Heart market launch schedule, accelerating its path from research to real-world impactproved that Caristo's CaRi-Heart technology can reveal hidden, high-risk markers of CAD progression — predicting heart attacks up to a decade before they strike. CaRi-Heart uses advanced AI to analyze perivascular fat captured in standard coronary CT angiography (CCTA) scans.  The technology reveals hidden coronary inflammation—a powerful but previously invisible predictor of heart attacks. Its proprietary FAI-Score™ and CaRi-Heart Risk Score give clinicians and patients a personalized assessment of cardiac mortality risk, informing earlier and more targeted treatment decisions. The CaRi-Heart technology is currently limited to research use in the United States.

Typically less than half of CPT applications are approved, and Caristo's success came well ahead of the CaRi-Heart market launch schedule, a feat made possible by strong support from medical societies such as the American College of Cardiology (ACC) and a growing clinical consensus that coronary inflammation is a modifiable and mission-critical risk factor for heart attack prevention.

In its public comment supporting the CPT application, the ACC wrote:

"The proposed service does more than characterizing tissue as it includes patient [risk] factors and provides a comprehensive risk assessment approach that ensures that the analysis is contextualized within the broader clinical picture, enhancing patient management decisions. The use of this service - the pericoronary fat attenuation index - shows great promise in risk stratification for preventive cardiology."

About Caristo Diagnostics
Caristo Diagnostics is a global leader in AI-powered heart disease detection. A spinout from the University of Oxford, Caristo's award-winning technology is transforming cardiovascular care by identifying hidden heart attack risks before symptoms appear. Backed by leading hospitals and scientists, Caristo is on a mission to save lives through early detection and personalized prevention. For more information, visit caristo.com. Find Caristo online on LinkedIn, YouTube, and X.

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