Xeris, Pharmaceuticals

Xeris Pharmaceuticals Stock Gains Momentum from Dual Catalysts

07.12.2025 - 17:56:04

Xeris Pharmaceuticals US98422E1038

Shares of Xeris Biopharma Holdings (XERS) are poised for a strong start to the trading week, buoyed by two significant weekend developments. A key patent allowance and inclusion on a prominent investment list provide a dual tailwind for the biopharmaceutical company.

In a notable show of market confidence, Xeris was added to Insider Monkey's "7 Hidden Multibagger Stocks to Invest In" list on Sunday. The selection criteria were stringent, requiring a market capitalization above $1 billion, a minimum return of 75% over the past year, and an upside potential of at least 30%. This inclusion highlights the growing investor appreciation for the company's financial trajectory.

Concurrently, the company secured a crucial patent allowance from the U.S. Patent and Trademark Office on Friday. The patent covers XP-8121, a weekly formulation of levothyroxine designed to treat hypothyroidism. This milestone substantially bolsters the intellectual property protection surrounding Xeris's development pipeline.

The company recently reinforced its long-term growth narrative at the Piper Sandler Healthcare Conference. Analyst models project the firm could achieve revenue of $440.9 million and a profit of $84.8 million by 2028.

Should investors sell immediately? Or is it worth buying Xeris Pharmaceuticals?

Technical Positioning and Analyst Sentiment

The market's reaction to these strategic moves is reflected in analyst ratings. The consensus for XERS remains "Moderate Buy." The average price target stands at $9.58, implying an upside of approximately 47% from the last closing price near $6.51. In November, Piper Sandler adjusted its target to $8.00 while maintaining a neutral stance.

From a technical perspective, the equity is trading within a defined range. Analysis from Stock Traders Daily identifies nearby support at $6.43 and an intermediate-term floor at $6.51. Immediate resistance levels are situated at $6.70 and $6.88. A breakout above these levels, potentially fueled by the patent news, could pave the way for a test of longer-term resistance near $9.54.

In after-hours trading on Friday, the stock showed early signs of accumulation, reaching as high as $6.78, a gain of 0.89%.

Weekly Trading Outlook

The combination of strengthened intellectual property and positive media recognition provides fundamental support. Market observers will monitor Monday's session to see if the share price can decisively break through the $6.70 resistance level on elevated volume. Looking ahead, the successful commercialization of its portfolio and the progression of XP-8121 through development will be critical to achieving the projected 2028 revenue targets. The focus now shifts to operational execution and regulatory progress.

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