CSTL, US14843C1053

Castle Biosciences stock reports 99.6% melanoma survival data

Published on 10/05/2026 at 13:01 | Editorial responsibility: Rafael Müller, Editor-in-Chief AD HOC NEWS

Castle Biosciences stock carries fresh melanoma evidence from September 30, with 2,799 patients across 29 U.S. centers. Q2 revenue reached USD 103.5 million.

CSTL, US14843C1053, Illustration mit AI erstellt.
CSTL, US14843C1053, Illustration mit AI erstellt.

Castle Biosciences stock (ISIN US14843C1053) was last at USD 35.56 on Nasdaq on October 2, 2026, with a 0.87 percent gain for the session. The company presented new DecisionDx-Melanoma findings at the European Academy of Dermatology and Venereology Congress, according to PR Newswire on September 30, 2026.

Melanoma data sharpen the story

The late-breaking study enrolled 2,799 patients at 29 U.S. centers. Among 676 patients who underwent sentinel lymph node biopsy, the observed positivity rate was 4.4 percent for low-risk results, compared with 22.8 percent for high-risk results, according to PR Newswire.

The most investor-relevant result was the five-year recurrence-free survival rate of 99.6 percent among 565 eligible patients with low-risk results who did not undergo the biopsy. A separate analysis of 687 transected melanomas showed five-year recurrence-free survival of 93.2 percent for Class 1A results versus 64.1 percent for Class 2B results, giving the company a clinical-data angle beyond routine staging.

Quarterly beat supports expansion

Castle Biosciences also enters the data discussion with a recent operating beat. For the second quarter ended June 30, 2026, revenue reached USD 103.5 million versus a USD 86.4 million consensus estimate, while adjusted loss was USD 0.07 per share versus an expected USD 0.40 loss, according to Investing.com.

The comparison matters because the company is funding a broader diagnostics portfolio while expanding beyond dermatology. The latest release also describes AdvanceAD-Tx, a 487-gene test for atopic dermatitis, alongside DecisionDx-Melanoma and the companys other molecular assays.

Analyst target stays above the quote

Lake Street analyst Thomas Flaten maintained a Buy rating and a USD 57.00 price target in a report published October 1, 2026, according to Markets Insider. The target lies 60.3 percent above the October 2 price, while the same report cited a Strong Buy consensus and an average target of USD 45.40.

Stock remains below yearly high

CSTL was last at USD 35.56 on Nasdaq on October 2, 2026 at 4:00 p.m. ET, with a session high of USD 35.92, a low of USD 34.76 and volume of 167,719 shares. Its 52-week range was USD 17.72 to USD 44.28, leaving the quote 19.7 percent below the high.

Castle Biosciences stock facts

  • Company: Castle Biosciences, Inc.
  • ISIN: US14843C1053
  • Ticker: CSTL
  • Trading venue: Nasdaq
  • Price (as of October 2, 2026, 4:00 p.m. ET): USD 35.56
  • Market capitalization: USD 1.1 billion (as of October 2, 2026)
  • 52-week range: USD 17.72-44.28 (as of October 2, 2026)
  • Sector / Industry: Healthcare / Medical Equipment, Supplies and Distribution

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