Immune, Thrombocytopenia

DelveInsight Business Research, LLP United Kingdom United States of America

17.01.2023 - 16:33:22

Immune Thrombocytopenia Market Size Growth to Shore Up at a CAGR of 5.4% During the Study Period , Assesses DelveInsight

report includes a comprehensive understanding of current treatment practices, immune thrombocytopenia emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].

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Key Takeaways from the Immune Thrombocytopenia Market Report

As per DelveInsight analysis, the immune thrombocytopenia market size in the 7MM was approximately USD 3,100 million in 2021.According to the assessment done by DelveInsight, the estimated total immune thrombocytopenia prevalent cases in the 7MM were approximately 184K in 2021. Globally, leading immune thrombocytopenia companies such as UCB Biopharma, Sanofi, Principia Biopharma, Argenx, Millennium Pharmaceuticals, Takeda, Biotest, GC Pharma,  UCB, HanAll Biopharma, Immunovant, Momenta Pharmaceuticals, Hutchison MediPharma, Cour Pharmaceutical Development, and others are developing novel immune thrombocytopenia drugs that can be available in the immune thrombocytopenia market in the coming years.The promising immune thrombocytopenia therapies in the pipeline include Rilzabrutinib (PRN-1008), Efgartigimod (ARGX-113), BIVV020, TAK-079, BT-595, GC5101B (GC5107A, IV-Globulin SN Inj. 10%), Rozanolixizumab, and others.In June 2022, Sanofi presented the efficacy and adverse events data from a phase I/II trial in Idiopathic thrombocytopenic purpura at the 27th Congress of the European Haematology Association (EHA-2022).In April 2022, Biotest submitted a marketing authorization application for IgG Next Generation in Germany.

Discover which therapies are expected to grab the major immune thrombocytopenia market share @ Immune Thrombocytopenia Market Report

Immune Thrombocytopenia Overview

Immune thrombocytopenia (ITP), also known as immune thrombocytopenic purpura or idiopathic thrombocytopenic purpura, is an autoimmune disorder that occurs when the body attacks and destroys its own platelets too quickly. ITP is now defined as any immune-related quantitative decrease in platelet count. Primary ITP, which accounts for 80% of cases, occurs when there is no secondary disease.

Common causes of secondary ITP are systemic lupus erythematosus (SLE), drugs, Hepatitis C, human immunodeficiency virus (HIV), Helicobacter pylori, Chronic Lymphocytic Leukemia, and other lymphoproliferative diseases, the antiphospholipid Syndrome, vaccines (Measles/Mumps/Rubella [MMR] most commonly), and Common Variable Immunodeficiency Disease (CVID) as well as other viruses, post-transfusion purpura, and Evans syndrome. These secondary causes account for about 20% of ITP cases.

Immune Thrombocytopenia Epidemiology Segmentation

DelveInsight estimates that there were approximately 184K prevalent cases of immune thrombocytopenia in the 7MM in 2021.

As per the analysis, the total diagnosed prevalent cases in the 7MM was estimated to be approximately 150K in 2021.

The immune thrombocytopenia market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:

Total Prevalent PopulationTotal Diagnosed Prevalent PopulationGender-specific Diagnosed Prevalence

Download the report to understand which factors are driving immune thrombocytopenia epidemiology trends @ Immune Thrombocytopenia Epidemiological Insights

Immune Thrombocytopenia Treatment Market 

The primary goal of immune thrombocytopenia treatment is to provide a platelet count that prevents major bleeding rather than to restore the platelet count to normal levels. The immune thrombocytopenia treatment varies greatly, and current international guidelines recommend several first- and second-line options, including some medicinal products that have not been approved in the EU for this specific condition.

The US Food and Drug Administration (FDA) approved avatrombopag (DOPTELET; Dova Pharmaceuticals) in June 2019 for the treatment of thrombocytopenia in adults with chronic ITP who had an inadequate response to a previous treatment. Avatrombopag was approved by the FDA in May 2018 for the treatment of thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure, making it the first drug to do so.

Moreover, immunosuppressants such as azathioprine (IMURAN), cyclosporine (NEORAL, Sandimmune), cyclophosphamide (CYTOXAN), and mycophenolate (CELLCEPT) have been used in single-agent regimens with some efficacy in the past. Still, their use has been limited due to drug-related toxicity and a low safety profile. However, there is growing evidence that combination chemotherapy can be used to treat chronic refractory ITP  to achieve greater efficacy and fewer adverse effects.

Furthermore, TAKECAB and NEXIUM capsules are approved in Japan to eradicate H. pylori in ITP patients. TAKECAB was approved in 2014, and NEXIUM capsules were approved in 2011. Further prospective trials may be able to improve the approach and overall outcomes.

To know more about immune thrombocytopenia guidelines, visit @ Immune Thrombocytopenia Management 

Immune Thrombocytopenia Pipeline Therapies and Key Companies

Rilzabrutinib (PRN-1008): Sanofi/Principia BiopharmaEfgartigimod (ARGX-113): ArgenxBIVV020: SanofiTAK-079: Millennium Pharmaceuticals/TakedaBT-595: BiotestGC5101B (GC5107A, IV-Globulin SN Inj. 10%): GC PharmaRozanolixizumab: UCB Biopharma

Learn more about the FDA-approved immune thrombocytopenia drugs @ Drugs for Immune Thrombocytopenia Treatment 

Immune Thrombocytopenia Market Dynamics

The immune thrombocytopenia market is anticipated to change during the forecasted period owing to the expected launch of emerging therapies. There are many pipeline therapies under development for the treatment of the patient with ITP. In addition, the rising number of product launches, combined with advancements in improving existing products, will drive the immune thrombocytopenia market growth.

Moreover, corticosteroid drugs with higher adaptability and cost-effectiveness will have a significant share in developed countries. Additionally, increased acceptance of TPO-RA as a second line of treatment will boost the immune thrombocytopenia market growth. Furthermore, the rising prevalence of ITP globally and increased awareness of the disease in the 7MM will drive the immune thrombocytopenia market growth during the forecast period.

However, several factors will hamper the growth of the immune thrombocytopenia market. The increased efficacy of alternative treatment options, such as platelet transfusion and surgery over available drugs, is expected to pose a challenge to immune thrombocytopenia market growth. Moreover, pediatric ITP treatment rates are declining, and the treatment paradigm is stagnant due to a lack of late-stage pipeline activities.

Furthermore, in some cases, the side effects of available drugs for the treatment of ITP force the patient to seek alternative treatment options. In addition, the patents on key TPO-RA branded drugs will expire by the end of 2022, lowering the cost of second-line therapy treatment and thus causing a dip in the growth of the immune thrombocytopenia market. Moreover, the following generics/biosimilars for the treatment of ITP are expected to erode immune thrombocytopenia market sales in the near future. 

Report Metrics

Details

Study Period

2019–2032

Coverage

7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan]

Base Year

2019

Immune Thrombocytopenia Market CAGR

5.4 %

Immune Thrombocytopenia Market Size in 2021

USD 3,100 Million

Key Immune Thrombocytopenia Companies

UCB Biopharma, Sanofi, Principia Biopharma, Argenx, Millennium Pharmaceuticals, Takeda, Biotest,
GC Pharma,  UCB, HanAll Biopharma, Immunovant, Momenta Pharmaceuticals, Hutchison MediPharma,
Cour Pharmaceutical Development, and others

Key Pipeline Immune Thrombocytopenia Therapies

Rilzabrutinib (PRN-1008), Efgartigimod (ARGX-113), BIVV020, TAK-079, BT-595, GC5101B (GC5107A,
IV-Globulin SN Inj. 10%), Rozanolixizumab, and others

 

Scope of the Immune Thrombocytopenia Market Report

Therapeutic Assessment: Immune Thrombocytopenia current marketed and emerging therapiesImmune Thrombocytopenia Market Dynamics: Immune Thrombocytopenia market drivers and barriers Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategiesUnmet Needs, KOL's views, Analyst's views, Immune Thrombocytopenia Market Access and Reimbursement

Discover more about immune thrombocytopenia drugs in development @ Immune Thrombocytopenia Clinical Trials

Table of Contents

1.

Immune Thrombocytopenia Market Key Insights

2.

Immune Thrombocytopenia Market Report Introduction

3.

Immune Thrombocytopenia Market Overview at a Glance

4.

Immune Thrombocytopenia Market Executive Summary

5.

Disease Background and Overview

6.

Immune Thrombocytopenia Treatment and Management

7.

Immune Thrombocytopenia Epidemiology and Patient Population

8.

Patient Journey

9.

Immune Thrombocytopenia Marketed Drugs

10.

Immune Thrombocytopenia Emerging Drugs

11.

Seven Major Immune Thrombocytopenia Market Analysis

12.

Immune Thrombocytopenia Market Outlook

13.

Potential of Current and Emerging Therapies

14.

KOL Views

15.

Immune Thrombocytopenia Market Drivers

16.

Immune Thrombocytopenia Market Barriers

17.

Unmet Needs

18.

SWOT Analysis

19.

Appendix

20.

DelveInsight Capabilities

21.

Disclaimer

22.

About DelveInsight

 

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