The DecisionBase 2012 report entitled Diabetic Retinopathy: Agents with Visual Acuity Benefits over Lucentis Will Find Commercial Success in the Diabetic Macular Edema Market finds that surveyed U.S. ophthalmologists and managed care organization (MCO) pharmacy directors agree that efficacy in improving visual acuity is one of the attributes that most influences their decisions regarding prescribing and formulary status determinations, respectively, in diabetic macular edema. Clinical data and the opinions of interviewed thought leaders indicate that current and emerging therapies have no advantage over sales-leading Lucentis on this attribute.

The report also finds that surveyed U.S. ophthalmologists indicate that they would prescribe Allergan/Sanwa Kagaku Kenkyusho?s dexamethasone intravitreal implant Ozurdex to 28 percent of their patients with diabetic macular edema. Decision Resources forecasts that Ozurdex will earn a 12 percent patient share in the U.S. diabetic macular edema market by 2020 owing to its safety and tolerability profile and the competition it will face from well-established anti-VEGF therapies by the time it enters the market.

According to insights from surveyed U.S. ophthalmologists and MCO pharmacy directors, less frequent dosing is one of the greatest unmet needs in diabetic macular edema.

?Clinical data and the opinions of thought leaders we interviewed indicate that Eylea, Ozurdex, and pSivida/Alimera Sciences? fluocinolone intravitreal implant Iluvien have demonstrated the potential to partially or significantly fulfill this unmet need,? said Decision Resources Analyst Kate Sullivan.

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